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“I expected a difference, but not so pronounced,” Conigliaro says. “I was also surprised that doses as low as what was used is the retrospective study would work that well. We had anticipated that bigger doses would be needed.” In the study, some patients received up to 20 milligrams of famotidine per day for five days intravenously, while others received it orally; when used for acid reflux, patients can take as much as 160 milligrams four times a day. Those who got the drug in the hospital fared better than those who did not, the study found. – 
The uncertainty of the COVID-19 pandemic has made our stomachs churn, and now, evidence suggests that intense heartburn may be linked with worse symptoms of the disease. Some drugs that neutralize stomach acid, such as famotidine, which President Donald Trump is taking, are associated with reduced severity, but others, such as Prilosec, correlate with higher infection rates and risk of death, at least in patients hospitalized with SARS-CoV-2 infections.

Stomach Acid & Heartburn Drugs Linked with COVID-19 Outcomes | The Scientist Magazine®

The drug was tied to significant reductions in in-hospital death and a combined death and intubation outcome in hospitalized patients in China, as well as an improvement in symptoms in a small case series of non-hospitalized patients, mostly in the U.S.

More Evidence Heartburn Drug May Help COVID-19 Patients | MedPage Today

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